Discovery activities range from studies of molecular and cellular processes to studies of the whole animal, in areas of cell and tissue growth, differentiation, regeneration, and numerous aspects of cancer biology. BMS faculty currently have active research programs in the areas of cancer biology; musculoskeletal biomechanics and skeletal adaptation; neural development, mechanisms of injury and regeneration; tissue dynamic spectroscopy; cellular and molecular screening; and high throughput analysis of cell function. Our directory of faculty research interests describes in more detail the exciting research that is conducted in BMS.
Dr. Shi is a professor of Basic Medical Sciences and Director for the Center for Paralysis Research. Dr. Shi is a medical scientist specializing in uncovering the mechanisms of central nervous system trauma and diseases and instituting new treatments through innovative experimentation and pioneering new strategies in the field. His research contributions includes originating the use of double sucrose gap technique for recording action potential conduction, establishing the methods of neuronal membrane resealing by polyethelyne glycol (PEG), and identifying acrolein as a key pathological factor in spinal cord injury and multiple sclerosis. His research interests also include using nanotechnology to improve drug delivery to nervous tissue and incorporating biomedical engineering principles to enhance neuronal repair and diagnosis. This includes designing innovative scaffolds to enhance neuronal regeneration and using bioadhesives for neuronal tissue repair.