Neuroscience


PVM Scholar Leads Groundbreaking Study of How the Brain’s Own Protective System Could Help Advance Treatment of Neurodegenerative Conditions

Friday, August 13th, 2021 - A labyrinthian network of blood vessels helps to maintain normal health by protecting the human brain from foreign contaminants. Unfortunately, this natural protection comes with a cost: While the maze keeps the brain safe, it is also an obstacle when treating brain damage or disease. Finding ways through the network could mean a drastic improvement in quality of life. Dr. Tiffany Lyle, assistant professor of veterinary anatomic pathology in the Purdue University College of Veterinary Medicine’s Department of Comparative Pathobiology and a member of Purdue’s Center for Cancer Research, is on a mission to do just that. She is the first scientist to map changes to the brain’s barrier during metastases of lung cancer and, more recently, she has produced the first comprehensive, molecular mapping of the network in relation to blast-induced traumatic brain injuries.



Indiana Fund’s Commercialization Award Supports Promising Technology Based on Work of PVM Faculty Member Riyi Shi

Friday, June 18th, 2021 - Technology related to the research of Purdue Veterinary Medicine neuroscientist Riyi Shi has received major new support as a means of providing new options for patients with neurological disease and pain.



Neuroscience Seminar Highlights Technologies for Brain Injuries, Vaccine Developments

Friday, April 2nd, 2021 - The same technology that helps treat traumatic brain injuries in athletes and soldiers may one day help doctors determine the effectiveness of vaccines on patients. This technology is among the neuroscience innovations and research in the spotlight as the Purdue University Center for Paralysis Research and Plexon Neurotechnology Systems present the Seminar for Neurotrauma and Diseases. The seminar series, which runs through April, features speakers from Purdue, Harvard Medical School, and the medical industry.



Purdue Innovators, Including Dr. Riyi Shi, Receive $1.3 Million Grant for Traumatic Brain Injury, Alzheimer’s Research

Friday, July 24th, 2020 - A team of Purdue University scholars led by professors from the Colleges of Science and Veterinary Medicine have received new support as they work to develop solutions to what U.S. military officials call an alarming trend in dementia among wounded soldiers. The same researchers also seek solutions to better treat Alzheimer’s disease. Innovators from several disciplines across the university make-up the Purdue research team that received a $1.3 million grant from the Department of Defense for their work in this area.



PVM Graduate Students Stand Out at Health and Disease Poster Session

Friday, March 27th, 2020 - When Purdue University hosted the seventh annual “Health and Disease: Science, Technology, Culture and Policy Research Poster Session” just before Spring Break, Purdue Veterinary Medicine graduate students showed-up in force. Held March 5 in the Purdue Memorial Union North Ballroom, the event offered cash prizes for the top three posters in each of six categories and PVM participants claimed three of the awards.



PVM-led Research on the Blood-Brain Barrier Featured on Cover of Scientific Journal

Friday, November 15th, 2019 - The most recently published research by the Comparative Blood-Brain Barrier Laboratory in Purdue Veterinary Medicine’s Department of Comparative Pathobiology, was featured on the cover of Oncotarget, a peer-reviewed bio-medical journal. Dr. Gozde Uzunalli, postdoctoral research associate, was the first author of the article, which highlighted how the blood-brain barrier transitions into the blood-tumor barrier when it is disturbed by cancer cells. The research was led by Dr. Tiffany Lyle, assistant professor of veterinary anatomic pathology.



BMS Faculty Member Finds that Urine Analysis Could Speed Diagnosis of Traumatic Brain Injury

Friday, September 13th, 2019 - A team of scientists led by Dr. Riyi Shi, Purdue Veterinary Medicine professor of basic medical sciences, has conducted research indicating that soldiers and athletes could have improved outcomes from traumatic brain injury through faster diagnosis using urine analysis.



Research Led by PVM’s Dr. Riyi Shi Utilizes World War II Antidote in Battle Against Parkinson’s Disease

Friday, December 7th, 2018 - A Purdue Veterinary Medicine professor is leading studies showing a World War II chemical weapon antidote to be effective in combating a new enemy: Parkinson’s disease.



Possible New Treatment for Spinal Cord Injuries Identified in Research Led by PVM Professor

Friday, June 15th, 2018 - Research led by a Purdue Veterinary Medicine scholar shows that an experimental drug has promise as a potential therapy for spinal cord injuries in animal studies. The compound, 4-aminopyridine-3-methanol, works in a similar way as a drug previously developed at Purdue, 4-aminopyridine (4-AP), which has been approved by the U.S. Food and Drug Administration to treat multiple sclerosis.



PVM Professor Leads Research that Identifies ‘Key Factor’ in Development of Parkinson’s Disease

Wednesday, April 25th, 2018 - Purdue University research team lead by Dr. Riyi Shi, professor in Purdue Veterinary Medicine’s Department of Basic Medical Sciences and the Weldon School of Biomedical Engineering, has identified a molecule that appears to play an important role in the development of Parkinson's disease. The discovery could lead to therapies, potentially including drugs currently on the market, as well as potentially facilitating earlier diagnosis and prevention of the neurological disorder.




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