Nelli Lab

Nelli Lab develops advanced 3D cell culture models and high-throughput diagnostics to address critical diseases affecting animals and humans.

Our research focuses on viral pathogenesis and host immune responses, particularly coronaviruses and influenza viruses at the animal-human interface.

We take pride in our innovative, high-throughput diagnostic solutions and in training the next generation of professionals.

Our Research

Building better models for infectious disease research

Three-dimensional cell cultures closely resemble the complex physiological functions of animal organs, making them valuable tools for studying organ development, modeling disease, discovering drugs, personalizing medicine, and investigating host-specific immune responses to pathogens.

Nelli Lab has established 3D cell cultures across multiple tissues and animal species to investigate molecular mechanisms at transcriptomic and proteomic levels.

Learn about organoids

Research Focus

3D cell cultures and diagnostic innovation

Research Projects

Our current research projects.

Publications

Our research findings.

Organoids

Models for studying how diseases or cancers develop in real-time.

Our Team

Meet the people behind the research at the Nelli Lab.

High-Throughput qPCR Assay Service

SmartChip qPCR and automation workflows.

News

The latest updates from the Nelli Lab.

We are actively looking for collaborative partners in academia and industry, as well as passionate students and post-doctoral researchers eager to contribute to infectious disease control through collaborative research and impactful training opportunities.

Nelli Lab

Purdue University College of Veterinary Medicine

High-throughput qPCR testing services

Running qPCR assays for 12 genes across 128 triplicate samples on a 96-well plate can require approximately 16 plates, around 30 mL of master mix, and about 32 hours to complete two-hour qPCR reactions.

Nelli Lab offers SmartChip qPCR assays that can accomplish the same task in about 4 hours, using only about 2 mL of master mix and eliminating inter-plate variability.

Learn more about our High-throughput qPCR testing services