Pre-Clinical Research

Within the Center for Clinical and Translational Research (CTR), pre-clinical animal studies are most often conducted in the Center's Pre-Clinical Research Laboratory (PCL). The mission of the PCL is to facilitate pre-clinical animal research, particularly of larger laboratory animals, and to create an environment of comparative and translational research learning. The PCL is a Purdue University and a CTSI-Indiana (Clinical and Translational Science Institute-Indiana) core facility and operates on a fee-for-service basis. All research conducted in the PCL is approved by the Purdue University Animal Care and Use Committee to ensure ethical use of research animals and compliance with the statutes of the Animal Welfare Act and the guidelines of the Public Health Service as issued in the Guide for the Care and Use of Laboratory Animals. The laboratory's facilities are accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC).

Pre-Clinical Research Laboratory
Lynn Hall Rm 1243
625 Harrison Street
West Lafayette, IN 47907

Pre-clinical studies – Precede clinical studies; usually in vitro and in vivo (animal) studies, where different aspects of the test article, including safety and efficacy, are evaluated. Animal models used in this stage of the translational continuum are usually so-called induced animal models. Successful pre-clinical studies may facilitate FDA approval. or further evaluation of the test article in clinical trials.

Test article - Any food additive, color additive, drug, biological product, electronic product, or medical device for human use subject to regulation under the Public Health Service Act.

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