Audrey Ruple, DVM, MS, PhD

Assistant Professor of One Health Epidemiology

Department of Comparative Pathobiology

Purdue University College of Veterinary Medicine
625 Harrison Street
West Lafayette, IN 47907

Phone: 765.496.0414
Email: aruple@purdue.edu

Purdue Comparative Oncology Program | Center for Animal Welfare Science | Purdue One Health Club | Follow Dr. Ruple on Twitter

Education

2014 - PhD | Colorado State University
2011 - MS | Colorado State University
2008 - DVM | Colorado State University
2002 - BS | Colorado State University

Certification

Diplomate, American College of Veterinary Preventive Medicine
Member of the Royal College of Veterinary Surgeons

Areas of Interest

Comparative Oncology
One Health Education
Companion Animal Epidemiology
Biosecurity and Infection Control

Selected Publications

– Ambrosius LA, Dhawan D, Ramos-Vara JA, Ruple A, Knapp, DW, Childress MO. Quantification and prognostic value of programmed cell death ligand-I in dogs with diffuse large B-cell lymphoma. American Journal of Veterinary Research. DOI: 10.2460/ajvr.79.6.643.

– Goeman V, Tinkler SH, Hammac GK, Ruple A. Evaluation of environmental sampling methods for detection of Salmonella enterica in a large animal veterinary hospital. Canadian Veterinary Journal. PMCID: PMC5855232.

– Childress MO, Ramos-Vara, JA, Ruple A. Retrospective analysis of factors affecting clinical outcome following CHOP-based chemotherapy in dogs with primary nodal diffuse large B-cell lymphoma. Veterinary and Comparative Oncology. DOI: 10.1111/vco.12364.

– Selmic LE, Ryan SD, Ruple A, Pass W, Withrow SJ. Tibial plateau leveling osteotomy increases the risk of proximal tibial osteosarcoma in dogs: A case-control study. Journal of American Veterinary Medical Association. DOI: 10.2460/javma.253.6.752.

– Widmar NJO, Dominick SR, Tyner WE, Ruple A. When is genetic modification socially acceptable? When it is used to advance human health through avenues other than food and nutrition. PLOS One. DOI: 10.1371/journal.pone.0178227.

– Widmar NJO, Dominick SR, Ruple A, Tyner WE. The influence of health concern on travel plans with focus on the Zika Virus in 2016. Preventive Medicine Reports. DOI: 10.1016/j.pmedr.2017.02.023.

– Robinette C, Saffran L, Ruple A, Deem SL. Zoos and Public Health: A partnership on the One Health frontier. One Health. DOI: 10.1016/j.onehlt.2016.11.003.

– Childress MO, Ramos-Vara JA, Ruple A. A randomized controlled trial of the effect of prednisone omission from a multidrug chemotherapy protocol on treatment outcome in dogs with peripheral nodal lymphomas. Journal of American Veterinary Medical Association. DOI: 10.2460/javma.249.9.1067.

– Ruple A, Avery AC, Morley PS. 2016. Differences in the geographic distribution of lymphoma subtypes in Golden retrievers in the USA. Veterinary and Comparative Oncology. DOI: 10.1111/vco.12258

– Ruple A, Morley PS. 2016. Risk factors associated with development of histiocytic sarcoma in Bernese mountain dogs. Journal of Veterinary Internal Medicine. DOI: 10.1111/jvim.13964

– Knapp DW, Ruple A, Ramos-Vera JA, Naughton JF, Fulkerson CM, Honkisz SI. 2016. A nonselective cyclooxygenase inhibitor enhances the activity of vinblastine in a naturally-occurring canine model of invasive urothelial carcinoma. Bladder Cancer. DOI: 10.3233/BLC-150044

– Ruple-Czerniak A, Aceto H, Bender JB, Paradis MR, Shaw SP, Van Metre DC, Weese JS, Wilson DA, Wilson J, Morley PS. 2014. Syndromic surveillance for evaluating the occurrence of healthcare-associated infections in equine hospitals. Equine Veterinary Journal. DOI: 10.1111/evj.12190.

– Ruple-Czerniak A, Bolte D, Burgess B, Morley PS. 2014. Comparison of two sampling and culture systems for detection of Salmonella enterica in the environment of a large animal hospital. Equine Veterinary Journal. DOI: 10.1111/evj.12193.

– Ruple-Czerniak A, Aceto H, Bender JB, Paradis MR, Shaw SP, Van Metre DC, Weese JS, Wilson DA, Wilson J, Morley PS. 2013. Using syndromic surveillance to estimate baseline rates for healthcare-associated infections in critical care units of small animal referral hospitals. Journal of Veterinary Internal Medicine. DOI: 10.1111/jvim.12190.

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