Evaluation of bacterial carbonic anhydrases as antibiotic therapeutic targets

Wednesday, October 25, 2023


He will present his work about identifying and optimizing carbonic anhydrase inhibitors with antibacterial activity against the pathogens vancomycin resistant enterococci and Neisseria gonorrhoeae. Structure-activity relationship optimization, target identification, ligand-bound structural evaluation of molecules to the targets, in vivo pharmacokinetics and efficacy will all be presented.

Speaker Details

Dr. Daniel Flaherty

Purdue University

Received PhD in Pharmaceutical Sciences from the University of Nebraska Medical Center under the direction of Dr. Jonathan Vennerstrom. Did a post-doc in medicinal chemistry at the University of Kansas under the direction of Dr. Jeffrey Aubé. Joined Purdue in the Department of Medicinal Chemistry and Molecular Pharmacology in July 2015. Currently an Associate Professor.