Shankar Thangamani, DVM, PhD
Assistant Professor, Microbiology

Department of Comparative Pathobiology
Purdue University College of Veterinary Medicine
625 Harrison Street
West Lafayette, IN 47907
Phone: 765.494.0763
Email: sthangam@purdue.edu
Thangamani Lab | Purdue Institute of Inflammation, Immunology and Infectious Diseases
Education
2016 - PhD | Purdue University
2009 - DVM | Madras Veterinary College, India
Areas of Interest
Microbiome, Metabolites and Host Defense in Fungal Pathogens
Antifungal Therapeutics
Experience
2021 - Present | Assistant Professor of Microbiology, Purdue University, West Lafayette, IN
2017 - 2021 | Assistant Professor of Microbiology, Midwestern University, College of Veterinary Medicine, Glendale, AZ
2010 - 2016 | Research Assistant, Department of Comparative Pathobiology, Purdue University, West Lafayette, IN
Selected Publications
Saif Hameed, Sandeep Hans, Shweta Singh, Ruby Dhiman, Ross Monasky, Ramendra Pati Pandey, Shankar Thangamani, and Zeeshan Fatima. Revisiting the Vital Drivers and Mechanisms of β-Glucan Masking in Human Fungal Pathogen, Candida albicans. Pathogens (* Corresponding authors)
Saif Hameed, Sandeep Hans, Ross Monasky, Shankar Thangamani*, Zeeshan Fatima*. Understanding Human Microbiota Offers Novel and Promising Therapeutic Options against Candida Infections. Pathogens (* Corresponding authors)
Ross Monasky, Sonia Villa, Thangamani S*. An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract. Journal of Visualized Experiments (JoVE) (* Corresponding author)
Sonia Villa, Mohammad Hamideh, Anthony Weinstock, Mohammad N Qasim, Tony R Hazbun, Adnane Sellam, Aaron D Hernday, Thangamani S*. Transcriptional control of hyphal morphogenesis in Candida albicans. FEMS Yeast Research. (* Corresponding author
Lawson S, Arumugam N*, Abdulrahman I. Almansour, Kumar R, Thangamani S*. Dispiropyrrolidine Tethered Piperidone Heterocyclic Hybrids with Broad-Spectrum Antifungal Activity Against Candida Albicans and Cryptococcus Neoformans. Bioorganic Chemistry (* Corresponding authors)
Gutierrez D, Weinstock A, Antharam VC, Gu H, Jasbi P, Shi X, Dirks B, Krajmalnik-Brown R, Maldonado J, Guinan J, Thangamani S*. Antibiotic-induced gut metabolome and microbiome alterations increase the susceptibility to Candida albicans colonization in the gastrointestinal tract. FEMS Microbiology Ecology (* Corresponding author)
Weinstock A, Arumugam N*, Abdulrahman I. Almansour, Kumar R, Thangamani S*. Discovery of diazahexa/hepta cyclic cage-like systems compounds with broad-spectrum antifungal activity against Candida and Cryptococcus species. RSC Advances (* Corresponding authors)
Guinan J, Wang S, Hazbun TR, Yadav H, Thangamani S*. Antibiotic-induced decreases in the levels of microbial-derived short-chain fatty acids correlate with increased gastrointestinal colonization of Candida albicans. Scientific Reports (* Corresponding author)
Bolous M, Arumugam N*, Almansour AI, Suresh Kumar R, Maruoka K, Antharam VC, Thangamani S*. Broad-spectrum antifungal activity of spirooxindolo-pyrrolidine tethered indole/imidazole hybrid heterocycles against fungal pathogens. Bioorganic and Medicinal Chemistry Letters (* Corresponding authors)
Villa P, Arumugam N*, Almansour AI, Suresh Kumar R, Mahalingam SM, Maruoka K, Thangamani S*. Benzimidazole tethered pyrrolo[3,4-b]quinoline with broad-spectrum activity against fungal pathogens. Bioorganic and Medicinal Chemistry Letters (* Corresponding authors)
Guinan J, Thangamani S*. Antibiotic-induced alterations in taurocholic acid levels promote gastrointestinal colonization of Candida albicans. FEMS Microbiology Letters (* Corresponding author)
Guinan J, Villa P, Thangamani S*. Secondary bile acids inhibit the growth and morphogenesis of Candida albicans. Pathogens and Disease (* Corresponding author)