What is Intensity Modulated Radiation Therapy (IMRT)

Intensity modulated radiation therapy (IMRT), is a state-of-the-art technique that uses the computer-controlled multi-leaf collimator to sculpt the radiation treatment beam to the unique tumor shape in order to deliver optimal doses of radiation directly to the tumor. Our targeted methods are much more precise than with conventional radiotherapy.

The level of normal tissue sparing achieved with IMRT is dramatic. While delivering the dose directly to the tumor, we can avoid important normal structures such as the eyes, brain, spinal cord, kidneys, lungs, or heart when the tumor is closely associated with any of these organs. Lower doses of radiation to normal tissues means a tremendous reduction in side effects. 

IMRT incorporates several beams coming from different angles to envelope the tumor and the dose intensity of each beam is modulated by changing the shape of the fields during treatment. Advanced imaging services using computed tomography (CT) and magnetic resonance imaging (MRI) are used to help deliver the radiation accurately and precisely. These diagnostic images of the patient’s tumor and surrounding anatomy are uploaded to an advanced treatment planning computer program (images below). This program then generates a treatment plan based on the individual patient’s tumor size, shape, and location within the body, along with the veterinary radiation oncologist’s dose prescription.

Our linear accelerator  is equipped with  a computer-controlled beam-shaping device called a multi-leaf collimator (MLC).  The MLC has 120 tungsten metal leaves for sculpting the radiation beam to deliver treatment doses to even the smallest of areas in accordance with the treatment plan.  With these developments we are able to treat types of cancer that were once considered untreatable with radiation therapy.  

The linear accelerator has the ability to rotate around the patient allowing us treat from multiple angles in order to administer high (optimal) doses of radiation to the tumor while sparing important healthy tissues.  A computer program controls the linear accelerator and the MLC (multi-leaf collimator) to match the patient’s treatment plan.  Accessories may be added to the treatment plan to improve dose distribution including wedges, blocks and tissue equivalent material (bolus).  Positional devices are also used to ensure accurate positioning of the patient, therefore ensuring the dose is delivered to the tumor, for consecutive treatments.  

Purdue University College of Veterinary Medicine, 625 Harrison Street, West Lafayette, IN 47907, (765) 494-7607

© 2019 Purdue University | An equal access/equal opportunity university | Copyright Complaints | Maintained by PVM Web Communications

If you have trouble accessing this page because of a disability, please contact PVM Web Communications at vetwebteam@purdue.edu.