{"id":7675,"date":"2020-02-21T11:55:44","date_gmt":"2020-02-21T16:55:44","guid":{"rendered":"https:\/\/qa.vet.purdue.edu\/news\/?p=7675"},"modified":"2020-02-21T11:55:44","modified_gmt":"2020-02-21T16:55:44","slug":"pvm-professor-helps-develop-new-technology-for-laser-driven-pathogen-detection","status":"publish","type":"post","link":"https:\/\/vet.purdue.edu\/news\/pvm-professor-helps-develop-new-technology-for-laser-driven-pathogen-detection.php","title":{"rendered":"PVM Professor Helps Develop New Technology for Laser-Driven Pathogen Detection"},"content":{"rendered":"\n<p>Professor J. Paul Robinson in Purdue Veterinary Medicine\u2019s\nDepartment of <a href=\"https:\/\/vet.purdue.edu\/bms\/index.php\" target=\"_blank\" rel=\"noopener noreferrer\">Basic Medical Sciences<\/a> worked with a team of Purdue researchers to\ndevelop new technology to help stop the spread of foodborne illnesses, which\nkill 3,000 people a year. The technology combines innovative assays with laser\npulses to detect these illnesses more efficiently. <\/p>\n\n\n\n<p>The research team developed a lanthanide-based assay coupled\nwith a laser that can be used to detect toxins and pathogenic E. coli in food\nsamples, water and a variety of industrial materials.&nbsp; The two key features of the new technology\nare the incorporation of lanthanides and simple lateral flow paper-based\nassays. <\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"502\" src=\"https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse-1024x502.jpg\" alt=\"diagram of laser pulse\" class=\"wp-image-7676\" srcset=\"https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse-1024x502.jpg 1024w, https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse-300x147.jpg 300w, https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse-768x376.jpg 768w, https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse-1536x752.jpg 1536w, https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse-2048x1003.jpg 2048w, https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse-480x235.jpg 480w, https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse-1320x646.jpg 1320w, https:\/\/vet.purdue.edu\/news\/wp-content\/uploads\/2020\/02\/laser-pulse.jpg 1300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption>Purdue innovators have developed a lanthanide-based assay coupled with a laser that can be used to detect toxins and pathogenic E. coli in food samples, water, and a variety of industrial materials. (Image provided)<\/figcaption><\/figure><\/div>\n\n\n\n<p>The Purdue team created a method for combining different heavy metals that, when linked to antibodies, can detect multiple agents in a single analysis. Their work is published in the January edition of <a href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-019-02347-3.pdf?_ga=2.4536947.1172919187.1581949682-1657661955.1559266353\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"Analytical and Bioanalytical Chemistry (opens in a new tab)\">Analytical and Bioanalytical Chemistry<\/a>.<\/p>\n\n\n\n<p>\u201cOur goal was to incorporate easily detectable elements into a paper-based assay which is low-cost and effective,\u201d said Dr. Robinson, who holds a joint appointment as the SVM Professor of Cytomics in the College of Veterinary Medicine and professor of biomedical engineering in Purdue\u2019s College of Engineering. \u201cDesigning a technology that is both low-cost but also accurate and can detect multiple antigens simultaneously was a critical factor in our decision to work on this problem.\u201d<\/p>\n\n\n\n<p>The innovators worked with the <a href=\"https:\/\/www.prf.org\/otc\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"Purdue Research Foundation Office of Technology Commercialization (opens in a new tab)\">Purdue Research Foundation Office of Technology Commercialization<\/a> (OTC) to patent the technology in the United States and in Europe. \u201cWe are very excited about the acceptance of the intellectual property as this will enhance the possibility of finding commercial partners,\u201d Dr. Robinson said. \u201cThe potential for moving this to handheld, field deployable use is something we see in the future.\u201d<\/p>\n\n\n\n<p>The approach uses a high-powered laser pulse to obliterate a\nsample, while simultaneously collecting the spectral signature of the resultant\nemission. These signals are then compared with a database that translates the\nsignals into an identification of the toxin or pathogen.<\/p>\n\n\n\n<p>The work published in the journal article shows the proof of\nprinciple and is the basis for significant expansion of the studies. The team\nis looking for partners. For more information, contact Dipak Narula of OTC at\ndnarula@prf.org and reference track code 2019-ROBI-68413.<\/p>\n\n\n\n<p>The U.S. Department of Agriculture Agricultural Research\nService (ARS) and Center for Food Safety Engineering (CFSE) provided funding\nfor the technology research in addition to Hatch Funds, which support\nagricultural research at land-grant institutions across the U.S. <\/p>\n\n\n\n<p>Click here to <a href=\"https:\/\/www.purdue.edu\/newsroom\/releases\/2020\/Q1\/new-technology-for-pathogen-detection-driven-by-lasers.html\">view\na complete news release<\/a>. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor J. Paul Robinson in Purdue Veterinary Medicine\u2019s Department of Basic Medical Sciences worked with a team of Purdue researchers to develop new technology to help stop the spread of foodborne illnesses, which kill 3,000 people a year. The technology combines innovative assays with laser pulses to detect these illnesses more efficiently.<\/p>\n","protected":false},"author":7,"featured_media":7676,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[41,29,11,1],"tags":[75,8,26,1562,56,1561,1563,150],"class_list":["post-7675","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty-staff","category-our-people","category-research","category-uncategorized","tag-bms","tag-faculty","tag-featured-story","tag-foodborne-illnesses","tag-homepage","tag-j-paul-robinson","tag-laser-pathogen-detection","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/posts\/7675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/comments?post=7675"}],"version-history":[{"count":5,"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/posts\/7675\/revisions"}],"predecessor-version":[{"id":7709,"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/posts\/7675\/revisions\/7709"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/media\/7676"}],"wp:attachment":[{"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/media?parent=7675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/categories?post=7675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vet.purdue.edu\/news\/wp-json\/wp\/v2\/tags?post=7675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}