1. Chang C-J, Freeman DJ, Wu H (2004). PTEN regulates Mdm2 expression through the P1 promoter. J Biol Chem 279, 29841-29848 
  2. Lei Q, Jiao J, Xin L, Chang C-J, Wang S, Gao J, Gleave ME, Witte ON, Liu X, Wu H (2006). NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. Cancer Cell 9, 367-378
  3. Chang C-J, Mulholland DJ, Valamehr B, Mosessian S, Sellers WR, Wu H (2008). PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression. Mol Cell Biology 28, 3281-3289 
  4. Guo W, Lasky J, Chang C-J, Mosessian S, Luis X, Shiu J, Iruela-Arispe ML, Wu H (2008). Multigenetic events collaboratively contribute to Pten-null leukemic stem cell formation. Nature 453, 529-533
  5. Yang, JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang J, Lai CC, Chang C-J, Hung MC, et al. (2008). ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nature Cell Biology 10, 138-148
  6. Ding Q, Huo L, Yang JY, Xia W, Wei Y, Lao Y, Chang C-J, Hung M C (2008). Downregulation of Mcl-1 through inhibiting Erk/Pin1 pathway by sorafenib facilitates chemosensitization in breast cancer. Cancer Research 68, 6109-6117
  7. Chang C-J*, Yang JY*, Wang Y, Wong KK, Engelman JA, Du Y, Andreeff M, Hortobagyi GN, Smith PD, Hung MC (2010). Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer.*equal contribution, Cancer Research 70, 4709-4718
  8. Chang C-J, Yang JY, Xia W, Chen CT, Xie X, Chao CH, Woodward WA, Hortobagyi GN, Hung MC (2011). EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling. Cancer Cell, 19, 86-100
  9. Chang C-J, Chao CH, Xia W, Yang JY, and Hung MC (2011). p53 regulates epithelial-mesenchymal transition (EMT) and stem cell properties through modulation of miRNAs. Nature Cell Biology 13, 317–323 (High-lighted by Faculty 1000)
  10. Chang C-J*, Ding Q*, Xie X, Xia W, Yang JY, Wang SC, Hung MC (2011). Genes that mediate colon cancer metastasis to liver.*equal contribution, Journal of Clinical Investigation, 121, 4526–4536 
  11. Lang JY, Hsu JL, Meric-Bernstam F, Chang C-J, Wang Q, Bao Y, Yamaguchi H, Xie X, Woodward WA, Yu D, Hortobagyi GN, Hung MC (2011). BIKDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment. Cancer Cell, 20, 341-356
  12. Liu M, Lee DF, Cheng CT, Yen CJ, Li LY, Lee HJ, Chang C-J, Hung MC (2012). IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression. Molecular Cell, 45, 171-184
  13. Chang C-J*, Tran LM*, Plaisier S, Wu S, Dang J, Mischel PS, Liao JS, Graeber TG, Wu H (2012). Determining PTEN functional status by network component deduced signature transcription factor activities.*equal contribution, Plos One, 7, e31053, 1-11
  14. Chang C-J, Hung MC (2012). The role of EZH2 in tumor progression. British Journal of Cancer, 106, 243-247 (Invited Review Article)
  15. Chao CH, Chang CC, Wu MJ, Ko HW, Wang D, Hung MC, Yang JY, C-J Chang (2014). MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis. Journal of Clinical Investigation, doi:10.1172/JCI73351.
  16. Chang CC, Wu MJ, Yang JY, Carmarillo I, Chang C-J (2015) Leptin-STAT3-G9a signaling promotes obesity-mediated breast cancer progression. Cancer Research, doi: 10.1158/0008-5472.CAN-14-3076.
  17. Li YH, Luo J, Mosley YY, Hedrick VE, Paul LN, Chang C-J, Zhang G, Wang YK, Banko MR, Brunet A, Kuang S, Wu JL, Chang C-J, Scott MP, Yang JY (2015). AMP activated protein kinase directly phosphorylates and destabilizes hedgehog pathway transcription factor GLI1 in medulloblastoma. Cell Reports 28, 599-609
  18. Wu MJ, Kim M, Chang C-J (2015) Regulation of microRNA-200c in cancer stem cells. Oncoscience, Vol.2 No. 9
  19. Wu MJ, Kim M, and Chang C-J (2016). Regulation of epithelial plasticity and cancer stemness via microRNAs. Journal of Molecular and Genetic Medicine 10:2 (
  20. Wu MJ and Chang C-J (2016). High Fat Diet-induced Breast Cancer Model in Rat. Bio-protocol 6(13): e1852.
  21. Wu MJ, Kim MR, Chen YS, Yang JY, Chang C-J (2017) Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKCζ pathway. Oncogene doi: 10.1038/onc.2016.467. 

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