Riyi Shi is a medical scientist specializing in uncovering the mechanisms of central nervous system trauma and diseases and instituting new treatments through innovative experimentation and pioneering new strategies in the field. His research contributions include originating the use of double sucrose gap technique for recording action potential conduction, establishing the methods of neuronal membrane resealing by polyethelyne glycol (PEG), and identifying acrolein as a key pathological factor in spinal cord injury and multiple sclerosis. His research interests also include using nanotechnology to improve drug delivery to nervous tissue and incorporating biomedical engineering principles to enhance neuronal repair and diagnosis. This includes designing innovative scaffolds to enhance neuronal regeneration and using bioadhesives for neuronal tissue repair.
Researchers have identified a key component in cigarette smoke that worsens pain in people with spinal cord injury, suggesting that a critical element within tobacco is responsible for such pain-inducing effects.
Findings support anecdotal information suggesting that smoking increases pain in patients with spinal cord injuries,” said Riyi Shi (pronounced Ree Shee), a professor of neuroscience and biomedical engineering in Purdue University's Department of Basic Medical Sciences, College of Veterinary Medicine and Weldon School of Biomedical Engineering. “This neuropathic pain could be felt in the leg and upper extremities, or in any part of the body.”
Dr. Riyi Shi
Mari Hulman George Endowed Professor of Applied Neuroscience
Director, Center for Paralysis Research
Department of Basic Medical Sciences
College of Veterinary Medicine
Weldon School of Biomedical Engineering