CPB 697 RESEARCH SEMINAR

DEPARTMENT OF COMPARATIVE PATHOBIOLOGY

Suzanne Pratt, DVM, MS

Graduate Student in Clinical Pathology

Department of Comparative Pathobiology

Purdue University

“Peritoneal Fluid From A Horse After Colic Surgery”

Thursday, October 11, 2007

VPTH 112

3:30 pm

ABSTRACT:

A 16-year-old castrated male Arabian horse was presented to the Purdue University Veterinary Teaching Hospital with a four hour history of colic. Initial examination provided strong evidence of a small intestinal obstruction. Surgery revealed a strangulating lipoma and 25 feet of small intestine was resected. Postoperatively, the horse developed an obstructive ileus which required a second laparotomy. Increased efforts were made to prevent further adhesion formation. Repeated abdominal lavage and administration of sodium carboxymethylcellulose were performed. One week following the second surgery, evaluation of peritoneal fluid revealed an exudate. Many macrophages contained magenta phagocytosed material. Extracellular, amorphous aggregates of magenta material were observed in the background. The phagocytosed and background material were consistent with the cytologic appearance of SCMC. This report is the first to demonstrate the cytologic appearance of SCMC in peritoneal fluid as well as the active phagocytosis associated with it.