CPB 697 RESEARCH SEMINAR

 

 

 

DEPARTMENT OF COMPARATIVE PATHOBIOLOGY

 

 

 

Jennifer McQuiston, DVM, MS, DACVPM

Leader, Zoonoses Team, Geographic Medicine and Health

Promotion Branch, Centers for Disease Control and Prevention

Atlanta, GA

 

 

 

Emergence Of Rocky Mountain Spotted Fever

In The Brown Dog Tick In Eastern Arizona

 

 

 

Thursday, January 25, 2007

VPTH 112

3:30 p.m.

 

Abstract:

Rocky Mountain spotted fever (RMSF), caused by Rickettsia rickettsii, is a tickborne disease that can cause severe or fatal illness in humans and dogs. In some cases, fatality rates may approach 20-30% in untreated cases. In the United States, the principal tick vectors of RMSF are Dermacentor variabilis (the American dog tick) and Dermacentor andersonii (the Rocky Mountain wood tick). Although the pathogen is distributed in ticks throughout much of the continental United States, RMSF is rarely reported from Arizona, which lies outside the range of the common tick vectors and has a hot, dry climate generally unfavorable to most species of ticks. However, from June 2002 through October 2004, 16 cases of RMSF, including 2 fatal cases, were identified from 2 small communities in rural eastern Arizona.

An investigation provided evidence that the outbreak in this Arizona community was likely caused by a novel tick vector, Rhipicephalus sanguineus (the brown dog tick). This outbreak most likely occurred because of unique ecological circumstances that supported an uncontrolled stray dog population, high densities of ticks, and frequent dog-human interactions, especially among children and dogs. The emergence of RMSF in previously unrecognized areas due to transmission by novel tick vectors, or due to habitat expansion of established vectors, should be recognized as a possibility by both medical and veterinary practitioners.

 

References:

1. Demma LJ, Traeger MS, Nicholson WL, Paddock CD, Blau DM, Eremeeva ME, et al. Rocky Mountain spotted fever from an unexpected tick vector in Arizona. NEJM 2005; 353(6):5870594