Purdue University

Purdue University

College of Veterinary Medicine
Comparative Pathobiology

PURDUE UNIVERSITY
Microbiology and Immunology Training Program
Department of Comparative Pathobiology


Postgraduate training programs for both the MS and PhD degrees are offered in the study of bacteriology, immunology, parasitology and virology.   Both degrees require independent research and preparation of an original thesis and require a minimum of two and four years, respectively.

Course work is selected jointly by the student and his/her major advisor, with the advice of the individual graduate advisory committee, to suit the student's background, interests and research problem.  Formal course work may be selected from offerings within the Department of Pathobiology and from other departments within the University. Courses in general biochemistry, molecular biology, immunology, microbial pathogenesis, statistical methods, bacteriology, virology and other discipline-based courses are often selected as part of individual plans of study. Assistance in preparation for Board Certification for the American College of Veterinary Preventive Medicine is available.


Limited numbers of teaching and research assistantships are available on a competitive basis.  Opportunity for gaining teaching experience is provided for all students, regardless of the nature of their stipend support.


The research focuses on the understanding of the molecular pathogenesis and immunology of veterinary and human infectious diseases as well as the development of novel diagnostic tests, therapeutics and methods to prevent infections. Investigations are conducted at the whole animal, tissue, cellular, and molecular levels and are supported by electron microscopy, flow cytometry, confocal microscopy, and imaging facilities within the school.  Protein synthesis, hybridoma, DNA-sequencing, mass spectroscopy, nuclear magnetic resonance, transgenic mouse facility, and other state of the art technologies are available on campus.

The Indiana State Animal Disease Diagnostic Laboratory provides a significant resource in the practical training of individuals interested in specialty board certification, e.g. microbiology and pathology.


Applicants must hold the BS or DVM degree or equivalent training in the biological sciences and be admitted by both the Department of Comparative Pathobiology and the Purdue University Graduate School.


We are particularly interested in recruiting women and minorities in our program because these groups are underrepresented in our professional disciplines.  Interested candidates should send letters of inquiry and requests for application forms to:
Barbara M. White, M.S.Ed.
Graduate Program Coordinator
and Administrative Assistant
Department of Comparative Pathobiology
Purdue University School of Veterinary Madicine
VPTH Building, 725 Harrison Street
West Lafayette, IN 47907-2027
Office Phone: 765-494-7542
Fax: 765-494-9830
Email: whiteb@purdue.edu
Purdue University is an Equal Opportunity/Equal Access Affirmative Action Employer/Educator


Microbiology and Immunology Section
Faculty and Research Interests

J.W. Camp, Ph.D., Professor of Veterinary Parasitology and Secretary of Faculties. Epidemiology and ecology of parasitic diseases; parasite induced changes in morphology, physiology, and behavior of invertebrate and vertebrate hosts; Identification of peptide sequences related to apicomplexan protein from Sarcocystis neurona.

S.A. Crist, Ph.D., Assistant Research Professor.

J.K. Davis, D.V.M., Ph.D., Professor of Laboratory Animal Medicine. Laboratory animal medicine, infectious disease, and animal models.

B.D. Elzey, Ph.D., Assistant Research Professor.

H. HogenEsch, D.V.M., Ph.D.,Professor of Immunopathology; Associate Dean for Research, Purdue Veterinary Medicine.  Diplomate, American College of Veterinary Pathologists.  Mucosal immunology and mucosal vaccines; adjuvants; dendritic cells; immunobiology of the skin.

K.R. Kazacos, D.V.M., Ph.D., Professor of Veterinary Parasitology; Director, Clinical Parasitology Laboratory.  Pathogenesis, pathology and epidemiology of parasitic diseases; immunobiology of helminth infections; parasitic zoonoses; visceral, ocular, and neural larva migrans; Baylisascaris spp.

Chang H. Kim, Ph.D., Section Head of Microbiology & Immunology, Professor of Immunology, University Faculty Scholar. Current studies in the lab include:
1. Roles of chemokine and chemokine receptors in trafficking of leukocytes in normal and diseased conditions; 2. Chemokine and chemokine receptors in forming immunity against pathogens and cancer cells. 3. Regulation of gene expression during T cell development to effector cells. Our favorite model cell types are various T cell subsets (conventional and CD1d-restricted) and hematopoietic stem and progenitor cells obtained from human and mice. For more information visit: http://web.ics.purdue.edu/~kim17/index.html

T.L. Lin, D.V.M., M.S., Ph.D., Professor of Veterinary Pathology; Head of Avian and Aquatic Section, Senior Veterinary Diagnostic Pathologist, Animal Disease Diagnostic Laboratory.   Diagnostic pathology; molecular pathology and immunohistopathology of infectious, toxic and neoplastic diseases; and avian, swine, and fish, laboratory animal pathology.

S.K. Mittal, D.V.M., M.S., Ph.D., Professor of Comparative Pathobiology, CPB Graduate Program Director, University Faculty Scholar, Member of Purdue Cancer Center, Member of Bindley Bioscience Center.   Viral expression vectors; recombinant vaccines; gene therapy; adenovirus; gene expression; role of adenovirus early region 1 and early region 3 in pathogenesis; mucosal immunity. Innate immunity, pandemic influenza including bird flu.

R.M. Pogranichniy, D.V.M., Ph.D., Associate Professor of Comparative Pathobiology, Diagnostic Virologist and Section Head of Virology and Serology, Animal Disease Diagnostic Laboratory. Veterinary diagnostic and infectious disease of production animals, emerging infectious diseases (diagnosis, pathogenesis, and vaccine development).

T. Ratliff, Ph.D., Professor of Comparative Pathobiology; Director of Purdue Cancer Center. Immunotherapy of Prostate Cancer, Immunotherapy of Bladder Cancer, Communication between innate and adaptive immune compartments via platelets, Prostate Inflammation, Bladder Inflammation.

M.N. Seleem, BVSc, MSc, PhD, Assistant Professor of Veterinary Microbiology. Targeted drug delivery for intracellular pathogens: Intracellular pathogens like Mycobacterium, Brucella, Salmonella and Listeria have developed various mechanisms to evade host defenses, and they can establish chronic infections. Treatment and eradication are difficult since infections are localized within phagocytic cells and most antibiotics, although highly active in-vitro, do not actively pass through cellular membranes. My research is focused on site-specific targeted drug delivery with increased bioavailability of antimicrobials/drugs using nanoparticles as carriers.

R. Vemulapalli, BVSc, MVSc, PhD, Head, Department of Comparative Pathobiology, Professor of Veterinary Immunology/Microbiology. Infectious diseases; microbial virulence factors; host immune responses; preventive and therapeutic vaccine development; immuno-modulation; bacterial vaccine vectors; nucleic acid vaccines; novel strategies to enhance vaccine efficacy.

T. Vemulapalli, DVM, MS, Clinical Assistant Professor in Comparative Pathobiology, Assistant Director, Veterinary Laboratory Animal Program, Diplomate, ACLAM


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